Is Oxidative Stress the Causality in the Develoment o HIV Virus

Most physicians believed that stress only lead to the development of a peptic ulcer; this is classic post positivistic scientific view. Ulcers are caused by H Pilori ; a gastrointestinal bacteria found in the stomach which is treatable with antibiotic treatment, how ever ,stress has the ability to cause non essential organ system disease (Zopolsky 2018) how does this occure? This occurs because when the individual is in the midst of a stressful event his or her primary physiologic function are the fight or flight response . This response is important to combat the stressful event in which the individual finds himself or herself ;and is guided by the sympathetic nervous system   meaning that essential systems such as the immune system are placed in the back burner while the stressful event is resolved . But what happens when stressers become multiplied ? , the immune system never really reactivates itself and  if it does; its not for long. This causes oxidative stress ; which is a very different type of stress, this type of stress uses distinct mechanisms of recovery and has the ability to cause devastating physiologic damage.  Some of the following pathologies and disease development associated with oxidative stress are  (1) heart failure (2) peptic ulcers (3) hair loss (4) cancer (5) obesity (6) mental illness , and (7) cell death. Is oxidative stress a factor in placing the individual in prime susceptibility for contracting HIV ? . Yes , because when  oxidative stress begin to occure cells lose an electron ; but to survive it retreaves an electron to replace the lose . If oxidative stress is in process and has no mechanism or electron supply to retrieve from then there is cell death . What can cause oxidative stress? Some of the following factors that cause oxidative stress are poor nutrition , ilicit drug use, IV rug use , illness , poverty and social stress . When these factors  occur alone they are not sufficient to cause oxidative stress which in turn cause cell death; however when these factors are almost all present in the life of an individual they do have the capacity to cause oxidative stress. that in turn cause place the person in a prime condition to contract HIV virus . Such as seen in an IV drug user who may have poor nutrition and homelessness , or a homosexual man with family issues who also uses drugs and suffers sexual repression. These examples are a few of the multiple which prevent the immune system to both function , prevent disease onset and  ever recovering its full function; because it is constantly being placed in the back burner .  To combat this type of stress antioxidants are necessary because they strengthen the cell from which electrons can be pulled when oxidative stress attempt to occur there by preventing the process of or onset of oxidative stress. Antioxidants are obtainable from fruits ,vegetables , supplements such as green tea.



References

Sapolsky , R (2017) The Science of Stress . Portrait of a Killer. National Geographics

E.J Corey , Czako , B & Kurti , L (207) Molecules and Medicine . Wiley Publishing