BioEngeenered Blood Vessels with the Capacity to Mimic Real Blood Vessels : Imlications for BBB

Researchers have developed engineered blood vessels that closely mimic the structure and function of human  blood vessels(NIH,2019) . These engendered vessels demonstrate promise in being safer and more effective in Grafts made from synthetic materials . which are a step in the right direction for patients with (E.S.R.D) End Stage Renal Failure .  What implications does this finding have though for the BBB or Blood Brain Barrier ? .  Based on the results of recent testing these Life Like vessels are now in the direction for clinical use . When we examine how these engineered vessels  can be beneficial in diagnostics and in E.S.R.D interventions . we can begin by estimating stating that 25 % of all human blood are filtered through the Renal System. we  can also assimilate that a common E.S.R.D patient have dietary limitations and liquid consumption that is a tough prescription with the average patient allowed to consume  only 32 oz of liquid per day on a hot summer day this prescription can be a challenge for any E.S.R.D patient particularly when these 32 oz include liquid used for cooking    The vessels are harvested from smooth muscle abundant in the uterus and other organs which also   may contribute to an increase in cost effectiveness . But what promise is there for BBB interventions to avert Hemiplegia in C.V.A patients ?  Lets examine the procedure involved in harvesting tissue .  Tissue is harvested in Burn victims . Skin Grafts in Dermatological such as Mohs surgical procedures to restore S.C.C and B.C.C excisions . these procedures take about one and a half to two months to fuse through colonization and skin cell fusion . Proteins and collagen play a vital role as does granulation . This how ever pertains to the psychopathology of  the dermis which has elasticity and a capacity to expand . Smooth muscle from internal organs have different proteins and a capacity for rejection because they are considered connective tissue  . so can these vessels be implanted in the BBB .quite possibly through microaggression procedures. the only foreseeable issue would be in neurological .implications because neuron in smooth tissue and striated tissue are different and distinct as are there function .


References

NIH (2019) VITA Program .Vascular Interventions / Innovations and Therapeutic Advances . (VITA) program .Retrieved from http://www.hihlbi.gov/science  /vascular interventioninnovation -and-therapeuticadvances