Issues in Public Health Law

Adolescents and Child Development : Holistic Care Perspectives

 In todays world adolescents find very few mentors and persons  of  guidance that will aid them  into transition  of young adulthood . Holis...

Sunday, January 13, 2019

CRISPR Cas 9 as a Tool in Addressing Heritable Disease . Public Health Applications.

Genome editing involves the deletion , insertion , or modification of the genome at specific sites within the genomes DNA sequence .The mere thought of the re Reconstruction of the DNA sequence provokes fear , confusion and differences in values , folkways and mores in society . The profound issues in health and well being that are witnessed in society today can not be denied ; in many instances these issues describe a  pathological society ( Principles of Public Health 2019) . Genome editing is guided by a set of laws that can be found within the GINA Act and this law should be available to society for instruction .The truth is that technology is well  advanced; such so that  plagues  in society  such as Opined use , Diabetics , and Heart disease can possibly be addressed through the use is Genome Editing . The chronic diseases mentioned above are all heritable diseases , , yes opioid  , heroin use as well as , alcoholism are heritable traits . In fact opioid addiction and heroin addiction are 20 % more heritable than diabetes which stands at being 34% heritable . Opioid addiction as well as heroin addiction are therefor about 54% heritable higher than many many other heritable diseases (NAP, 2016) .  CRISPER Cas 9 as well as TALENS  offer hope in addressing many of the chronic diseases mentioned above , is cost effective and precise  in clinical practice and public health endevours . The molecular mechanism found in CRISPER Cas 9 allows for the recognition of damaged DNA stand targets it then gRNA compliments the the located site of damage where Cas 9 can cleave the area with great specificity( CDC.gov ,2019) There are two DNA repair types , the first is Non Homologous end joining and the second repair type is Homology Directed Repair which utilizes Codone Manipulation . PBSS or Prescription Behavior Surveillance   is an excellent way of prevention deaths from opioid overdose , but one must also take into consideration heredity in disease manifestation  , phenotype development and in gene expression ( CDC.gov,2019) .  The clinical application of Gene Editing are currently being applied to plant DNA and to research involving Crops , but the same  molecular mechanisms of action may soon be applied to health care practice . When addressing critical issues in Public Health it is best to offer the consumer a wide variety of solutions for any given problem (NASH ,2019)


References

Nash , J 2019) Game Theory . Retrieved from http://www. Columbia.edu

CDC (2019) Drug Overdose . Centers for Disease Control Retrieved from http://www.cdc.gov/drigoverdose/pdf/pdssReports-072017.pdf

Genetic Alliance (2019) CRISPR CAS 9 . Retrieved from http;//www.geneticalliance  .org.uk

NAP(2019) Pathways in Addiction . National Academies Press

     

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